Identification of natural killer cell-characteristic genes in atherosclerosis based on bioinformatics analysis
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-98524-9
Abstract: Atherosclerosis (AS), a chronic inflammatory disease with autoimmune components, represents the predominant pathological change underlying cardiovascular diseases. Natural killer (NK) cells, pivotal actors in the innate immune system, play intricate regulatory roles in AS. Our… read more here.
Keywords: analysis; atherosclerosis; characteristic genes; cell ... See more keywords
Identification of the Characteristic Genes and their Roles in Lung Adenocarcinoma Lymph Node Metastasis through Machine Learning Algorithm
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/1968829
Abstract: Background Lymph node metastasis is an important route of lung cancer metastasis and can significantly affect the survival of lung cancer. Methods All the analysis was conducted out in the R software. Expression profile and… read more here.
Keywords: metastasis; lung adenocarcinoma; node metastasis; analysis ... See more keywords
Predicting the Progress of Tuberculosis by Inflammatory Response-Related Genes Based on Multiple Machine Learning Comprehensive Analysis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Immunology Research"
DOI: 10.1155/2023/7829286
Abstract: Background Tuberculosis (TB), caused by the bacterium Mycobacterium tuberculosis, affects approximately one-quarter of the global population and is considered one of the most lethal infectious diseases worldwide. The prevention of latent tuberculosis infection (LTBI) from… read more here.
Keywords: tuberculosis; inflammatory response; progression; analysis ... See more keywords
Screening of characteristic genes in ulcerative colitis by integrating gene expression profiles
Sign Up to like & getrecommendations! Published in 2021 at "BMC Gastroenterology"
DOI: 10.1186/s12876-021-01940-0
Abstract: Background This study aimed to screen the feature modules and characteristic genes related to ulcerative colitis (UC) and construct a support vector machine (SVM) classifier to distinguish UC patients. Methods Four datasets that contained UC… read more here.
Keywords: gene expression; characteristic genes; ulcerative colitis; gene ... See more keywords
Characteristic genes and immune landscape of interstitial cystitis
Sign Up to like & getrecommendations! Published in 2025 at "PLOS One"
DOI: 10.1371/journal.pone.0320249
Abstract: Background Interstitial cystitis (IC) was still a disease with the exclusive diagnosis and lacked an effective gold standard. It was of great significance to find diagnostic markers for IC. Our study was aimed to screen… read more here.
Keywords: interstitial cystitis; immune landscape; genes immune; characteristic genes ... See more keywords
Identification of susceptibility modules and characteristic genes to osteoarthritis by WGCNA.
Sign Up to like & getrecommendations! Published in 2024 at "Annales de biologie clinique"
DOI: 10.1684/abc.2024.1913
Abstract: The susceptibility modules and characteristic genes of patients with osteoarthritis (OA) were determined by weighted gene co-expression network analysis (WGCNA), and the role of immune cells in OA related microenvironment was analyzed. GSE98918 and GSE117999… read more here.
Keywords: gene expression; susceptibility modules; characteristic genes; immune ... See more keywords
Using machine learning to find genes associated with sudden death
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.1042842
Abstract: Objective To search for significant biomarkers associated with sudden death (SD). Methods Differential genes were screened by comparing the whole blood samples from 15 cases of accidental death (AD) and 88 cases of SD. The… read more here.
Keywords: associated sudden; machine learning; death; sudden death ... See more keywords
Bioinformatics analysis of the expression of potential common genes and immune-related genes between atrial fibrillation and chronic kidney disease
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2025.1521722
Abstract: Research objective This study is based on bioinformatics analysis to explore the co-expressed differentially expressed genes (DEGs) between atrial fibrillation (AF) and chronic kidney disease (CKD), identify the biomarkers for the occurrence and development of… read more here.
Keywords: disease; analysis; key characteristic; characteristic genes ... See more keywords
Landscape of RNA-binding proteins in diagnostic utility, immune cell infiltration and PANoptosis features of heart failure
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1004163
Abstract: Objective: Heart failure remains a global public health problem linked to rising morbidity and mortality. RNA-binding proteins (RBPs) are crucial regulators in post-transcriptionally determining gene expression. Our study aimed to comprehensively elucidate the diagnostic utility… read more here.
Keywords: heart failure; immune cell; heart; utility ... See more keywords
Development of a prognostic model for hepatocellular carcinoma based on microvascular invasion characteristic genes by spatial transcriptomics sequencing
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1529569
Abstract: Microvascular invasion (MVI) is an independent risk factor for the recurrence and metastasis of hepatocellular carcinoma (HCC), associated with poor prognosis. Thus, MVI has significant clinical value for the treatment selection and prognosis assessment of… read more here.
Keywords: hcc; risk; prognosis; characteristic genes ... See more keywords
Integrated bioinformatics analysis uncovers characteristic genes and molecular subtyping system for endometriosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.932526
Abstract: Objective: Endometriosis is a chronic inflammatory estrogen-dependent disease with the growth of endometrial tissues outside the uterine cavity. Nevertheless, the etiology of endometriosis is still unclear. Integrated bioinformatics analysis was implemented to reveal the molecular… read more here.
Keywords: endometriosis; bioinformatics analysis; analysis; integrated bioinformatics ... See more keywords