Toll-like receptor 4 signaling pathway is correlated with pathophysiological characteristics of AML patients and its inhibition using TAK-242 suppresses AML cell proliferation.
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DOI: 10.1016/j.intimp.2020.107202
Abstract: PURPOSE Acute myeloid leukemia (AML) is one of the most severe blood cancers. Many studies have revealed that inflammation has an essential role in the progression of hematopoietic malignancies. Since the toll-like receptor 4 (TLR4)… read more here.
Keywords: characteristics aml; tak 242; aml patients; pathophysiological characteristics ... See more keywords