Investigation of the molecular characteristics of bisindole inhibitors as HIV-1 glycoprotein-41 fusion inhibitors.
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DOI: 10.1016/j.ejmech.2018.10.048
Abstract: In previous work, we described 6-6'-bisindole compounds targeting a hydrophobic pocket on the N-heptad repeat region of viral glycoprotein-41 as effective inhibitors of HIV-1 fusion. Two promising compounds with sub-micromolar IC50's contained a benzoic acid… read more here.
Keywords: characteristics bisindole; investigation molecular; benzoic acid; molecular characteristics ... See more keywords