Characteristics and molecular mechanisms through which SGLT2 inhibitors improve metabolic diseases: A mechanism review.
Sign Up to like & getrecommendations! Published in 2022 at "Life sciences"
DOI: 10.1016/j.lfs.2022.120543
Abstract: Metabolic diseases, such as diabetes, gout and hyperlipidemia are global health challenges. Among them, diabetes has been extensively investigated. Type 2 diabetes mellitus (T2DM), which is characterized by hyperglycemia, is a complex metabolic disease that… read more here.
Keywords: inhibitors improve; metabolic diseases; molecular mechanisms; mechanisms sglt2 ... See more keywords
Characteristics of the molecular electron density, delocalization effect and hydrogen bonding interaction of nitroxoline
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2017.03.125
Abstract: Abstract The density functional theoretical (DFT) calculations have been carried out at the B3LYP/6-311G(d,p) level of theory for nitroxoline monomer and dimer molecule. The dimer molecule formed between two nitroxoline subunits has the largest stability,… read more here.
Keywords: hydrogen; delocalization; characteristics molecular; density ... See more keywords
The changing characteristics and molecular profiles of papillary thyroid carcinoma over time: a systematic review
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DOI: 10.18632/oncotarget.12885
Abstract: Background The genetic alterations of papillary thyroid carcinoma (PTC) have been reported to change over the past few decades. We performed this systematic review to further examine the trends and modifications of patient demographic, clinicopathological… read more here.
Keywords: papillary thyroid; molecular profiles; systematic review; time ... See more keywords
Virulence Characteristics and Molecular Typing of Carbapenem-Resistant ST15 Klebsiella pneumoniae Clinical Isolates, Possessing the K24 Capsular Type
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DOI: 10.3390/antibiotics12030479
Abstract: Klebsiella pneumoniae is an opportunistic pathogen that frequently causes nosocomial and community-acquired (CA) infections. Until now, a limited number of studies has been focused on the analyses of changes affecting the virulence attributes. Genotypic and… read more here.
Keywords: virulence characteristics; klebsiella pneumoniae; virulence; characteristics molecular ... See more keywords
Clinical Characteristics and Molecular Patterns of RET-Rearranged Lung Cancer in Chinese Patients.
Sign Up to like & getrecommendations! Published in 2019 at "Oncology research"
DOI: 10.3727/096504018x15344979253618
Abstract: RET rearrangement has been proven as an oncogenic driver in patients with lung cancer. However, the prevalence, clinical characteristics, molecular features, and therapeutic options in RET-rearranged patients remain unclear, especially in Chinese lung cancer patients.… read more here.
Keywords: lung; lung cancer; clinical characteristics; characteristics molecular ... See more keywords