Synthesis and Characterization of Andrographolide Derivatives as Regulators of βAPP Processing in Human Cells.
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DOI: 10.3390/molecules26247660
Abstract: Alzheimer's disease (AD) is a devastating neurodegenerative disorder, one of the main characteristics of which is the abnormal accumulation of amyloid peptide (Aβ) in the brain. Whereas β-secretase supports Aβ formation along the amyloidogenic processing… read more here.
Keywords: characterization; synthesis characterization; andrographolide derivatives; derivatives regulators ... See more keywords