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Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00082
Abstract: This paper discusses the biological and three-dimensional molecular structure of the novel, nonpeptide Y2R antagonist, SF-11 [ N-(4-ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide]. Pharmacokinetic studies in a rat model indicated that, following intraperitoneal dosing, SF-11 crossed the blood-brain barrier and…
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Keywords:
brain penetrant;
penetrant neuropeptide;
characterization brain;
brain ... See more keywords