Articles with "characterization cathepsin" as a keyword



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Characterization of Cathepsin B in Mediating Silica Nanoparticle-Induced Macrophage Pyroptosis via an NLRP3-Dependent Manner

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Published in 2022 at "Journal of Inflammation Research"

DOI: 10.2147/jir.s371536

Abstract: Introduction Silica nanoparticles (SiNPs) are one of the most widely used inorganic nanomaterials, and exposure to SiNP has been demonstrated to induce pulmonary inflammation, primarily promoted by the NLRP3-mediated macrophage pyroptosis. However, mechanisms underlying the… read more here.

Keywords: macrophage pyroptosis; ctsb; expression nlrp3; pyroptosis ... See more keywords