Characterization of clinical human prostate cancer lesions using 3.0‐T sodium MRI registered to Gleason‐graded whole‐mount histopathology
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.26336
Abstract: Overtreatment of prostate cancer (PCa) is a healthcare issue. Development of noninvasive imaging tools for improved characterization of prostate lesions might reduce overtreatment. read more here.
Keywords: prostate; characterization clinical; histopathology; prostate cancer ... See more keywords
Functional characterization and clinical significance of super‐enhancers in lung adenocarcinoma
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DOI: 10.1002/mc.23419
Abstract: Super‐enhancers (SEs) are important transcriptional regulators in tumorigenesis; however, the functional characterization and clinical significance of SEs in lung adenocarcinoma (LUAD) remain unclear. By using H3K27ac ChIP‐seq data of two LUAD cell lines and eight… read more here.
Keywords: functional characterization; clinical significance; characterization clinical; super enhancers ... See more keywords
Further characterization of clinical and laboratory features in VEXAS syndrome: large‐scale analysis of a multicentre case series of 116 French patients *
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Dermatology"
DOI: 10.1111/bjd.20805
Abstract: A new autoinflammatory syndrome related to somatic mutations of UBA1 was recently described and called VEXAS syndrome (‘Vacuoles, E1 Enzyme, X‐linked, Autoinflammatory, Somatic syndrome’). read more here.
Keywords: features vexas; clinical laboratory; syndrome large; laboratory features ... See more keywords
Discovery, characterization and clinical utility of prostaglandin agonists for the treatment of glaucoma
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DOI: 10.1111/bph.14327
Abstract: Topical ophthalmic formulations of analogues of the endogenous arachidonic acid cyclooxygenase metabolite, PGF2α, are the standard of care treatment for the blinding disease glaucoma. These are the most potent and efficacious medical therapies for lowering… read more here.
Keywords: utility prostaglandin; clinical utility; treatment; glaucoma ... See more keywords
In vitro characterization and clinical evaluation of skin hydration by two formulations mimicking the skin’s natural components
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DOI: 10.1111/jdv.17900
Abstract: We have developed innovative base formulations that were designed to mimic the skin with respect to its components and galenic structure. Components include water, proteins, lipids, sugars and minerals. read more here.
Keywords: skin hydration; hydration two; evaluation skin; clinical evaluation ... See more keywords
Characterization of Clinical Isolates of Talaromyces marneffei and Related Species, California, USA
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DOI: 10.3201/eid2509.190380
Abstract: Talaromyces marneffei and other Talaromyces species can cause opportunistic invasive fungal infections. We characterized clinical Talaromyces isolates from patients in California, USA, a non–Talaromyces-endemic area, by a multiphasic approach, including multigene phylogeny, matrix-assisted laser desorption/ionization… read more here.
Keywords: isolates talaromyces; characterization clinical; talaromyces marneffei; california usa ... See more keywords