Identification and characterization of the Cucurbitacins, a novel class of small-molecule inhibitors of Tropomyosin receptor kinase a
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DOI: 10.1186/s12906-019-2709-z
Abstract: BackgroundNGF-TrkA is well known to play a key role in propagating and sustaining pruritogenic signals, which form the pathology of chronic pruritus. Inhibition of NGF-TrkA is a known strategy for the treatment of pruritus. In… read more here.
Keywords: kinase; trka; identification characterization; characterization cucurbitacins ... See more keywords