Genetic characterization of human metapneumovirus identified through community and facility‐based surveillance of infants in Dhaka, Bangladesh
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25351
Abstract: Acute respiratory infection (ARI) is a leading cause of morbidity and mortality in children in low and middle‐income countries. Human metapneumovirus (hMPV) is one of the most common viral etiological agents for ARIs in children. read more here.
Keywords: metapneumovirus identified; identified community; characterization human; metapneumovirus ... See more keywords
Isolation and Characterization of Human Alveolar Type II Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8570-8_7
Abstract: Alveolar type II (ATII) cells synthesize, store, and secrete pulmonary surfactant and restore the epithelium after damage to the alveolar epithelium. Isolation of human ATII cells provides a valuable tool to study their function under… read more here.
Keywords: isolation characterization; characterization human; human alveolar; alveolar type ... See more keywords
Isolation and Characterization of Human Lung Myeloid Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8570-8_9
Abstract: Multiparameter flow cytometry of human lungs allows for characterization, isolation, and examination of human pulmonary immune cell composition, phenotype, and function. Here we describe an approach to process lung tissues and then utilize a base… read more here.
Keywords: isolation characterization; immune cell; characterization human; human lung ... See more keywords
High-Throughput Discovery and Characterization of Human Transcriptional Effectors
Sign Up to like & getrecommendations! Published in 2020 at "Cell"
DOI: 10.1016/j.cell.2020.11.024
Abstract: Thousands of proteins localize to the nucleus; however, it remains unclear which contain transcriptional effectors. Here, we develop HT-recruit, a pooled assay where protein libraries are recruited to a reporter, and their transcriptional effects are… read more here.
Keywords: human transcriptional; characterization human; throughput discovery; transcriptional effectors ... See more keywords
Bioinformatic prediction and functional characterization of human KIAA0100 gene
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical Analysis"
DOI: 10.1016/j.jpha.2016.09.003
Abstract: Our previous study demonstrated that human KIAA0100 gene was a novel acute monocytic leukemia-associated antigen (MLAA) gene. But the functional characterization of human KIAA0100 gene has remained unknown to date. Here, firstly, bioinformatic prediction of… read more here.
Keywords: kiaa0100 gene; human kiaa0100; functional characterization; characterization human ... See more keywords
Characterization of human monoclonal antibodies that neutralize multiple poliovirus serotypes.
Sign Up to like & getrecommendations! Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.03.038
Abstract: Following the eradication of wild poliovirus (PV), achieving and maintaining a polio-free status will require eliminating potentially pathogenic PV strains derived from the oral attenuated vaccine. For this purpose, a combination of non-cross-resistant drugs, such… read more here.
Keywords: antibodies neutralize; monoclonal antibodies; human monoclonal; cross neutralization ... See more keywords
Proteomic characterization of the human lens and Cataractogenesis
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Proteomics"
DOI: 10.1080/14789450.2021.1913062
Abstract: ABSTRACT Introduction The goal of this review is to highlight the triumphs and frontiers in measurement of the lens proteome as it relates to onset of age-related nuclear cataract. As global life expectancy increases, so… read more here.
Keywords: lens cataractogenesis; age related; proteomic characterization; characterization human ... See more keywords
Functional characterization of the human tRNA methyltransferases TRMT10A and TRMT10B
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa353
Abstract: Abstract The TRM10 family of methyltransferases is responsible for the N1-methylation of purines at position 9 of tRNAs in Archaea and Eukarya. The human genome encodes three TRM10-type enzymes, of which only the mitochondrial TRMT10C… read more here.
Keywords: trmt10b; functional characterization; characterization human; trmt10a trmt10b ... See more keywords
Functional characterization of the human Cdk10/Cyclin Q complex
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DOI: 10.1098/rsob.210381
Abstract: Cyclin-dependent kinases (CDKs) are key players in cell cycle regulation and transcription. The CDK-family member Cdk10 is important for neural development and can act as a tumour suppressor, but the underlying molecular mechanisms are largely… read more here.
Keywords: cdk10; characterization human; cell cycle; functional characterization ... See more keywords
Phenotypic characterization of human peripheral γδT‐cell subsets in glioblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology and Immunology"
DOI: 10.1111/1348-0421.13016
Abstract: The antitumoral contribution of γδT cells depends on their activation and differentiation into effectors. This depends on different molecules and membrane receptors, which conditions their physiology. This study aimed to determine the phenotypic characteristics of… read more here.
Keywords: phenotypic characterization; characterization human; expression; cd56 nkg2d ... See more keywords
Characterization of human respiratory syncytial virus (RSV) isolated from HIV‐exposed‐uninfected and HIV‐unexposed infants in South Africa during 2015‐2017
Sign Up to like & getrecommendations! Published in 2020 at "Influenza and Other Respiratory Viruses"
DOI: 10.1111/irv.12727
Abstract: RSV is a leading cause of lower respiratory tract infection in infants. Monitoring RSV glycoprotein sequences is critical for understanding RSV epidemiology and viral antigenicity in the effort to develop anti‐RSV prophylactics and therapeutics. read more here.
Keywords: respiratory syncytial; syncytial virus; rsv; characterization human ... See more keywords