Generation and characterization of humanized synergistic neutralizing antibodies against SARS‐CoV‐2
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27801
Abstract: The emerging coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is the causative agent of coronavirus disease 2019 (COVID‐19), which has become a severe threat to global public health and local economies. In this study,… read more here.
Keywords: characterization humanized; synergistic neutralizing; humanized synergistic; generation characterization ... See more keywords
Development and in vitro characterization of a humanized scFv against fungal infections
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0276786
Abstract: The resistance and the birth of new intrinsic and multidrug-resistant pathogenic species like C. auris is creating great concern in the antifungal world. Given the limited drug arsenal and the lack of effectiveness of the… read more here.
Keywords: characterization humanized; vitro characterization; development vitro; scfv fungal ... See more keywords
Generation and characterization of a humanized ACE2 rat model for the study of SARS-CoV-2 and COVID-19
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2025.1680273
Abstract: Our goal was to generate new rat strains for the study of human pathogenic viruses such as SARS-CoV-2 that use ACE2 for entry into host cells. An over-expression rat model was generated using random transgenesis… read more here.
Keywords: sars cov; generation characterization; rat; characterization humanized ... See more keywords
Characterization of Humanized Mouse Model of Organophosphate Poisoning and Detection of Countermeasures via MALDI-MSI
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25115624
Abstract: Organophosphoate (OP) chemicals are known to inhibit the enzyme acetylcholinesterase (AChE). Studying OP poisoning is difficult because common small animal research models have serum carboxylesterase, which contributes to animals’ resistance to OP poisoning. Historically, guinea… read more here.
Keywords: mouse; maldi msi; model; characterization humanized ... See more keywords