Abstract 7132: Preclinical characterization of LAE119, a novel PARP1 selective inhibitor and trapper
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DOI: 10.1158/1538-7445.am2024-7132
Abstract: Current PARP inhibitors primarily target PARP1/2 and demonstrate high efficacy against tumors with deficiencies in homologous recombination repair, such as those with BRCA mutations. However, these inhibitors are also associated with significant hematological toxicities. Studies… read more here.
Keywords: preclinical characterization; characterization lae119; parp1; lae119 ... See more keywords