Reduction of endotoxicity in Bordetella bronchiseptica by lipid A engineering: Characterization of lpxL1 and pagP mutants
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DOI: 10.1080/21505594.2021.1929037
Abstract: ABSTRACT Whole-cell vaccines against Gram-negative bacteria commonly display high reactogenicity caused by the endotoxic activity of lipopolysaccharide (LPS), one of the major components of the bacterial outer membrane. Underacylation of the lipid A moiety of… read more here.
Keywords: lpxl1; bordetella bronchiseptica; endotoxicity; characterization lpxl1 ... See more keywords