Structural Characterization of a Macrocyclic Peptide Modulator of the PD-1/PD-L1 Immune Checkpoint Axis
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DOI: 10.3390/molecules26164848
Abstract: The clinical success of PD-1/PD-L1 immune checkpoint targeting antibodies in cancer is followed by efforts to develop small molecule inhibitors with better penetration into solid tumors and more favorable pharmacokinetics. Here we report the crystal… read more here.
Keywords: structural characterization; immune checkpoint; macrocyclic peptide; characterization macrocyclic ... See more keywords