Structural characterization of the mitochondrial Ca2+ uniporter provides insights into Ca2+ uptake and regulation
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.102895
Abstract: Summary The mitochondrial uniporter is a Ca2+-selective ion-conducting channel in the inner mitochondrial membrane that is involved in various cellular processes. The components of this uniporter, including the pore-forming membrane subunit MCU and the modulatory… read more here.
Keywords: uniporter; uptake regulation; characterization mitochondrial; ca2 uptake ... See more keywords
Comprehensive molecular characterization of mitochondrial genomes in human cancers
Sign Up to like & getrecommendations! Published in 2020 at "Nature Genetics"
DOI: 10.1038/s41588-019-0557-x
Abstract: Mitochondria are essential cellular organelles that play critical roles in cancer. Here, as part of the International Cancer Genome Consortium/The Cancer Genome Atlas Pan-Cancer Analysis of Whole Genomes Consortium, which aggregated whole-genome sequencing data from… read more here.
Keywords: sequencing data; comprehensive molecular; characterization mitochondrial; mitochondrial genomes ... See more keywords
The Regulation and Characterization of Mitochondrial-Derived Methylmalonic Acid in Mitochondrial Dysfunction and Oxidative Stress: From Basic Research to Clinical Practice
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/7043883
Abstract: Methylmalonic acid (MMA) can act as a diagnosis of hereditary methylmalonic acidemia and assess the status of vitamin B12. Moreover, as a new potential biomarker, it has been widely reported to be associated with the… read more here.
Keywords: regulation characterization; characterization mitochondrial; methylmalonic acid; oxidative stress ... See more keywords
Spectroscopic Characterization of Mitochondrial G-Quadruplexes
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23020925
Abstract: Guanine quadruplexes (G4s) are highly polymorphic four-stranded structures formed within guanine-rich DNA and RNA sequences that play a crucial role in biological processes. The recent discovery of the first G4 structures within mitochondrial DNA has… read more here.
Keywords: dna; mitochondrial quadruplexes; characterization mitochondrial; rna ... See more keywords
Characterization of Mitochondrial Prohibitin in Opsariichthys bidens and Its Potential Functions in Spermatogenesis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23137295
Abstract: Spermatogenesis is the intricate and coordinated process by which spermatogonia develop into haploid differentiated spermatozoa. Mitochondria are essential for spermatogenesis, and prohibitin (PHB) is closely associated with mitochondrial structure and function during spermatogenesis. Although PHB… read more here.
Keywords: potential functions; spermatogenesis; phb; prohibitin ... See more keywords