Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2- d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5.
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DOI: 10.1021/acs.jmedchem.8b01606
Abstract: The availability of a chemical probe to study the role of a specific domain of a protein in a concentration- and time-dependent manner is of high value. Herein, we report the identification of a highly… read more here.
Keywords: bay 885; probe; potent highly; characterization potent ... See more keywords