Articles with "characterization protac" as a keyword



Characterization of PROTAC specificity and endogenous protein interactomes using ProtacID

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Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-63357-7

Abstract: Here we describe ProtacID, a flexible BioID (proximity-dependent biotinylation)-based approach to identify PROTAC-proximal proteins in living cells. ProtacID analysis of VHL- and CRBN-recruiting PROTACs targeting a number of different proteins (localized to chromatin or cellular… read more here.

Keywords: protac; characterization protac; endogenous protein; protein interactomes ... See more keywords