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Published in 2019 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.13793
Abstract: Demonstrate the presence of cytochrome P450 (CYP) and UDP‐glucuronosyltransferase (UGT) proteins and mRNAs in isolated human plasma exosomes and evaluate the capacity for exosome‐derived biomarkers to characterize variability in CYP3A4 activity.
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Keywords:
characterize variability;
plasma extracellular;
drug;
derived biomarkers ... See more keywords