Effects of charge-modifying mutations in histone H2A α3-domain on nucleosome stability assessed by single-pair FRET and MD simulations
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DOI: 10.1038/s41598-017-13416-x
Abstract: Nucleosomes are important for chromatin compaction and gene regulation; their integrity depends crucially on the structural properties of the histone tails. Recent all-atom molecular dynamics simulations revealed that removal of the N-terminal tails of histone… read more here.
Keywords: charge modifying; histone h2a; nucleosome stability; h2a ... See more keywords