Arginine‐Modified Nanostructured Lipid Carriers with Charge‐Reversal and pH‐Sensitive Membranolytic Properties for Anticancer Drug Delivery
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201600693
Abstract: The ability to escape endo/lysosomal trafficking is critically important to prevent entrapment of nanomedicines in lysosomes and to achieve maximum therapeutic efficacy of drugs delivered to cells through endocytosis. In this study, a novel pH-sensitive… read more here.
Keywords: lipid carriers; charge reversal; microscopy; drug delivery ... See more keywords
Electrophoretic mobility of carboxyl latex particles: effects of hydrophobic monovalent counter-ions
Sign Up to like & getrecommendations! Published in 2017 at "Colloid and Polymer Science"
DOI: 10.1007/s00396-017-4219-1
Abstract: To investigate the effect of hydrophobicity on the charge reversal of colloidal particles, we measured and analyzed the electrophoretic mobility (EPM) of carboxyl latex particles in mixed electrolytes solutions containing potassium chloride KCl and tetraphenylphosphonium… read more here.
Keywords: charge reversal; latex particles; carboxyl latex; charge ... See more keywords
Novel carrier-free, charge-reversal and DNA-affinity nanodrugs for synergistic cascade cancer chemo-chemodynamic therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2021.08.121
Abstract: The combination of chemotherapy (CT) and chemodynamic therapy (CDT) is an emerging therapeutic strategy for tumors; however, its therapeutic efficacy is usually impaired by the shortage of high-efficiency intracellular catalysts for CDT and the poor… read more here.
Keywords: charge reversal; novel carrier; carrier free;
Combination of SCX fractionation and charge-reversal derivatization facilitates the identification of non-tryptic peptides in C-terminomics.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.9b00264
Abstract: The proteome wide, mass spectrometry based identification of protein C-termini is hampered by factors such as poor ionization efficiencies, low yielding labeling strategies or the need for enrichment procedures. We present a bottom-up proteomics workflow… read more here.
Keywords: protein; combination; charge reversal; identification ... See more keywords
Degradable Bactericide Constructed Using a Charge-Reversal Surfactant against Plant Pathogenic Bacteria.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c24588
Abstract: Plant bacterial diseases are serious problems in agriculture, posing threats to global food security and the agricultural economy. Here, a degradable agricultural bactericide AMC-10 constructed using a charge-reversal surfactant, from being positively charged to negatively… read more here.
Keywords: constructed using; charge reversal; reversal surfactant; plant ... See more keywords
Induced Self-Assembly and Disassembly of Alkynylplatinum(II) 2,6-Bis(benzimidazol-2'-yl)pyridine Complexes with Charge Reversal Properties: "Proof-of-Principle" Demonstration of Ratiometric Förster Resonance Energy Transfer Sensing of pH.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c05677
Abstract: A series of pH-responsive alkynylplatinum(II) 2,6-bis(benzimidazol-2'-yl)pyridine (bzimpy) complexes with charge-reversal properties was synthesized, and the supramolecular assemblies between conjugated polyelectrolyte, PFP-OSO3-, and [Pt{bzimpy(TEG)2}{C≡C-C6H3-(COOH)2-3,5}]Cl (1) have been studied using UV-vis absorption, emission, and resonance light scattering… read more here.
Keywords: bis benzimidazol; transfer; alkynylplatinum bis; energy ... See more keywords
pH-Induced Charge-Reversal Amphiphile with Cancer Cell-Selective Membrane-Disrupting Activity.
Sign Up to like & getrecommendations! Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.8b06660
Abstract: A charge-reversal amphiphile exhibiting charge conversion from negative to positive induced by pH is reported. It selectively kills cancer cells through cell membrane disruption. This amphiphile comprising an alkyl chain and anionic headgroup of acid-labile… read more here.
Keywords: charge reversal; charge; cancer; cell ... See more keywords
A modular assembly pH-sensitive charge reversal siRNA delivery system.
Sign Up to like & getrecommendations! Published in 2018 at "Biomaterials science"
DOI: 10.1039/c8bm01062e
Abstract: Cationic lipids and polymers are the most common non-viral vectors for siRNA delivery; however, their intense positively charged character may give rise to serum-triggered aggregation, immune activation, inflammation stimulation and grievous toxicity. An ocean of… read more here.
Keywords: charge reversal; sirna delivery; modular assembly; delivery ... See more keywords
Charge reversal and swelling in saccharide binding polyzwitterionic phenylboronic acid-modified poly(4-vinylpyridine) nanoparticles
Sign Up to like & getrecommendations! Published in 2019 at "Polymer Chemistry"
DOI: 10.1039/c9py00938h
Abstract: We present the synthesis and characterization of zwitterionic poly(4-vinylpyridine) nanoparticles quaternized with phenylboronic acid (QxPVP-PBA) whose size and surface charge can be tuned by varying the saccharide and the degree of quaternization. read more here.
Keywords: charge reversal; phenylboronic acid; vinylpyridine nanoparticles; poly vinylpyridine ... See more keywords
Charge reversal hairpin peptide modified synergy therapeutic nanoplatforms for tumor specific drug shuttling.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm00817c
Abstract: Given the distinct pathological features of neoplasm tissues, multifunctional responsive nanocarriers have been recently considered as promising candidates to optimize the chemotherapy regime. As a result, we propose a graphene oxide-based pH-responsive drug delivery system… read more here.
Keywords: tumor specific; hairpin peptide; charge reversal; graphene oxide ... See more keywords
pH-Sensitive and Charge-Reversal Polymeric Nanoplatform Enhanced Photothermal/Photodynamic Synergistic Therapy for Breast Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.836468
Abstract: As reported, breast cancer is one of the most common malignancies in women and has overtaken lung cancer as the most commonly diagnosed cancer worldwide by 2020. Currently, phototherapy is a promising anti-tumor therapy due… read more here.
Keywords: cancer; breast cancer; charge reversal; therapy ... See more keywords