Quantifying Permeation of Small Charged Molecules across Channels: Electrophysiology in Small Volumes
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DOI: 10.1021/acsomega.8b01611
Abstract: A major bottleneck in the development of small-molecule antibiotics is to achieve good permeability across the outer membrane in Gram-negative bacteria. Optimization with respect to permeability surprisingly lacks appropriate methods. Recently, we proposed to use… read more here.
Keywords: quantifying permeation; across channels; permeation small; molecules across ... See more keywords