A specific negatively charged sequence confers intramolecular regulation on Munc13-1 function in synaptic exocytosis.
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DOI: 10.1073/pnas.2508915122
Abstract: Significance Munc13-1 is a master regulator of neurotransmitter release, which features a long low-complexity region in its N terminus. Here, we identified a functional motif in this region, termed polyE, which is unique to Munc13-1… read more here.
Keywords: munc13; sequence confers; negatively charged; charged sequence ... See more keywords