Impact of nonalcoholic fatty liver disease status change on antiviral efficacy of nucleos(t)ide analogues in HBeAg‐positive chronic hepatitis B
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28501
Abstract: Data on the dynamic changes in chronic hepatitis B (CHB) patients with nonalcoholic fatty liver disease (NAFLD) during antiviral therapy are scarce. We aimed to investigate the evolution of NAFLD status change in CHB patients… read more here.
Keywords: nonalcoholic fatty; chb patients; hbeag positive; chronic hepatitis ... See more keywords
Diagnosis of significant liver fibrosis in patients with chronic hepatitis B using a deep learning-based data integration network
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology International"
DOI: 10.1007/s12072-021-10294-4
Abstract: Chronic hepatitis B virus (CHB) infection remains a major global health burden and the non-invasive and accurate diagnosis of significant liver fibrosis (≥ F2) in CHB patients is clinically very important. This study aimed to assess… read more here.
Keywords: diagnosis significant; chb patients; chronic hepatitis; deep learning ... See more keywords
Intrahepatic innate immune response pathways are downregulated in untreated chronic hepatitis B.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2016.12.024
Abstract: BACKGROUND & AIMS Hepatitis B virus (HBV) persistence and the pathobiology of chronic HBV (CHB) infections result from the interplay between viral replication and host immune responses. We aimed to comprehensively analyse the expression of… read more here.
Keywords: immune; hepatitis; hbv; chronic hepatitis ... See more keywords
Dynamic metabolic profiles for HBeAg seroconversion in chronic hepatitis B (CHB) patients by gas chromatography-mass spectrometry (GC-MS).
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2021.114349
Abstract: Chronic hepatitis B (CHB) remains a major public health problem globally. HBeAg seroconversion is a vital hallmark for the improvement of CHB. The plasma metabolic profile has not been clear in CHB patients and searching… read more here.
Keywords: seroconversion; hbeag seroconversion; metabolic profiles; chb patients ... See more keywords
Modulation of bile acid profile by gut microbiota in chronic hepatitis B
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.14951
Abstract: Chronic hepatitis B (CHB) is a global epidemic disease that may progress to fibrosis, cirrhosis and hepatocellular carcinoma. The role of the liver‐bile acid‐microbiota axis in CHB remains unclear. The aims of this study are… read more here.
Keywords: chb; fibrosis; gut microbiota; bile acid ... See more keywords
Fatty liver is associated with advanced fibrosis but does not predict adverse outcomes in patients with chronic hepatitis B
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13361
Abstract: Hepatic steatosis is increasingly common and has been implicated in progression of liver fibrosis in chronic hepatitis B (CHB) patients. We aimed to investigate the impact of hepatic steatosis on liver fibrosis and clinical outcomes… read more here.
Keywords: associated advanced; hepatic steatosis; fibrosis; chb patients ... See more keywords
Hepatic steatosis and metabolic risk factors among patients with chronic hepatitis B: The multicentre, prospective CAP‐Asia study
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13796
Abstract: We aimed to compare the severity of liver disease, metabolic profile and cardiovascular disease (CVD) risk of chronic hepatitis B (CHB) patients with and without hepatic steatosis and patients with non‐alcoholic fatty liver disease (NAFLD).… read more here.
Keywords: chb patients; patients hepatic; steatosis; risk ... See more keywords
Impact of NAFLD on the outcome of patients with chronic hepatitis B in Asia
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DOI: 10.1111/liv.15252
Abstract: Hepatitis B virus (HBV) infection and nonalcoholic fatty liver disease (NAFLD) are two major causes of chronic liver disease (CLD) that can cause liver cirrhosis and hepatocellular carcinoma (HCC). It is a trend to superimpose… read more here.
Keywords: chb patients; chronic hepatitis; concurrent nafld; hepatitis ... See more keywords
Quest for immunological biomarkers in the management of CHB patients
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DOI: 10.1136/gutjnl-2023-329437
Abstract: Control of hepatitis B virus (HBV) infection requires functional virusspecific T cells, yet clinical management of patients with chronic HBV infection (CHB) relies exclusively on the assessment of virological (HBVDNA, HBsAg) and biochemical (alanine transaminase… read more here.
Keywords: chb patients; cell; chb; hbvspecific cell ... See more keywords
Profiling of Peripheral TRBV and CD4+CD25+ Treg in CHB Patients with HBeAg SC during TDF Treatment
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Immunology Research"
DOI: 10.1155/2023/1914036
Abstract: Background It is lacking that markers could predict the prognosis of chronic hepatitis B (CHB) subjects during antiviral treatment, and the related cellular immune mechanism is not fully evaluated. Aim To explore the comprehensive profile… read more here.
Keywords: chb patients; treg; chb; treatment ... See more keywords
Beneficial Effects of Bushen Formula Combined with Enticavir on Chronic Hepatitis B Patients with Suboptimal Response to Enticavir by Regulating B-Cell Differentiation
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DOI: 10.1159/000491891
Abstract: Background/Aims: To investigate the clinical effects of the combination therapy with Bushen Formula (BSF) plus enticavir (ETV) on chronic hepatitis B (CHB) patients with suboptimal response to ETV and explore the regulatory mechanisms of BSF… read more here.
Keywords: suboptimal response; patients suboptimal; treatment; group ... See more keywords