Impact of nonalcoholic fatty liver disease status change on antiviral efficacy of nucleos(t)ide analogues in HBeAg‐positive chronic hepatitis B
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DOI: 10.1002/jmv.28501
Abstract: Data on the dynamic changes in chronic hepatitis B (CHB) patients with nonalcoholic fatty liver disease (NAFLD) during antiviral therapy are scarce. We aimed to investigate the evolution of NAFLD status change in CHB patients… read more here.
Keywords: nonalcoholic fatty; chb patients; hbeag positive; chronic hepatitis ... See more keywords
Application of Interpretable Machine Learning Models to Predict the Risk Factors of HBV‐Related Liver Cirrhosis in CHB Patients Based on Routine Clinical Data: A Retrospective Cohort Study
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Medical Virology"
DOI: 10.1002/jmv.70302
Abstract: Chronic hepatitis B (CHB) infection represents a significant global public health issue, often leading to hepatitis B virus (HBV)‐related liver cirrhosis (HBV‐LC) with poor prognoses. Early identification of HBV‐LC risk is essential for timely intervention.… read more here.
Keywords: hbv; risk; machine; chb ... See more keywords
Diagnosis of significant liver fibrosis in patients with chronic hepatitis B using a deep learning-based data integration network
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DOI: 10.1007/s12072-021-10294-4
Abstract: Chronic hepatitis B virus (CHB) infection remains a major global health burden and the non-invasive and accurate diagnosis of significant liver fibrosis (≥ F2) in CHB patients is clinically very important. This study aimed to assess… read more here.
Keywords: diagnosis significant; chb patients; chronic hepatitis; deep learning ... See more keywords
Intrahepatic innate immune response pathways are downregulated in untreated chronic hepatitis B.
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DOI: 10.1016/j.jhep.2016.12.024
Abstract: BACKGROUND & AIMS Hepatitis B virus (HBV) persistence and the pathobiology of chronic HBV (CHB) infections result from the interplay between viral replication and host immune responses. We aimed to comprehensively analyse the expression of… read more here.
Keywords: immune; hepatitis; hbv; chronic hepatitis ... See more keywords
Dynamic metabolic profiles for HBeAg seroconversion in chronic hepatitis B (CHB) patients by gas chromatography-mass spectrometry (GC-MS).
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2021.114349
Abstract: Chronic hepatitis B (CHB) remains a major public health problem globally. HBeAg seroconversion is a vital hallmark for the improvement of CHB. The plasma metabolic profile has not been clear in CHB patients and searching… read more here.
Keywords: seroconversion; hbeag seroconversion; metabolic profiles; chb patients ... See more keywords
The remodeling of B-cell subsets was correlated with the clearance of hepatitis B antigen during pegylated IFN α-2a therapy in CHB patients
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DOI: 10.1080/07853890.2025.2463569
Abstract: Abstract Background B-cell may participate in the cellular immune process of hepatitis B antigen clearance. However, the function and specific mechanism of B-cell during interferon-pegylated interferon α-2a (Peg-IFN-α) treatment in chronic hepatitis B (CHB) patients… read more here.
Keywords: peg ifn; ifn treatment; cell; clearance ... See more keywords
Identifying liver cirrhosis in patients with chronic hepatitis B: an interpretable machine learning algorithm based on LSM
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DOI: 10.1080/07853890.2025.2477294
Abstract: Abstract Background Chronic hepatitis B (CHB) is a common cause of liver cirrhosis (LC), a condition associated with an unfavourable prognosis. Therefore, timely diagnosis of LC in CHB patients is crucial. Objective This study aimed… read more here.
Keywords: chb patients; cirrhosis; machine; chb ... See more keywords
Modulation of bile acid profile by gut microbiota in chronic hepatitis B
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DOI: 10.1111/jcmm.14951
Abstract: Chronic hepatitis B (CHB) is a global epidemic disease that may progress to fibrosis, cirrhosis and hepatocellular carcinoma. The role of the liver‐bile acid‐microbiota axis in CHB remains unclear. The aims of this study are… read more here.
Keywords: chb; fibrosis; gut microbiota; bile acid ... See more keywords
Fatty liver is associated with advanced fibrosis but does not predict adverse outcomes in patients with chronic hepatitis B
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DOI: 10.1111/jvh.13361
Abstract: Hepatic steatosis is increasingly common and has been implicated in progression of liver fibrosis in chronic hepatitis B (CHB) patients. We aimed to investigate the impact of hepatic steatosis on liver fibrosis and clinical outcomes… read more here.
Keywords: associated advanced; hepatic steatosis; fibrosis; chb patients ... See more keywords
Hepatic steatosis and metabolic risk factors among patients with chronic hepatitis B: The multicentre, prospective CAP‐Asia study
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DOI: 10.1111/jvh.13796
Abstract: We aimed to compare the severity of liver disease, metabolic profile and cardiovascular disease (CVD) risk of chronic hepatitis B (CHB) patients with and without hepatic steatosis and patients with non‐alcoholic fatty liver disease (NAFLD).… read more here.
Keywords: chb patients; patients hepatic; steatosis; risk ... See more keywords
Impact of NAFLD on the outcome of patients with chronic hepatitis B in Asia
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DOI: 10.1111/liv.15252
Abstract: Hepatitis B virus (HBV) infection and nonalcoholic fatty liver disease (NAFLD) are two major causes of chronic liver disease (CLD) that can cause liver cirrhosis and hepatocellular carcinoma (HCC). It is a trend to superimpose… read more here.
Keywords: chb patients; chronic hepatitis; concurrent nafld; hepatitis ... See more keywords