CHCHD2 and CHCHD10-related neurodegeneration: molecular pathogenesis and the path to precision therapy.
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DOI: 10.1042/bst20221365
Abstract: In the last decade, dominant mutations in the mitochondrial protein CHCHD10 (p.R15L and p.S59L) and its paralog CHCHD2 (p.T61I) were shown to cause familial amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD), respectively, with phenotypes… read more here.
Keywords: precision therapy; chchd10; chchd10 related; related neurodegeneration ... See more keywords