Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Cardiology"
DOI: 10.1001/jamacardio.2018.1470
Abstract: Importance Human genetic studies have indicated that plasma lipoprotein(a) (Lp[a]) is causally associated with the risk of coronary heart disease (CHD), but randomized trials of several therapies that reduce Lp(a) levels by 25% to 35%… read more here.
Keywords: risk; change; chd risk; level ... See more keywords
Live-Born Major Congenital Heart Disease in Denmark: Incidence, Detection Rate, and Termination of Pregnancy Rate From 1996 to 2013
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Cardiology"
DOI: 10.1001/jamacardio.2018.2009
Abstract: Importance The occurrence of major congenital heart disease (CHD) is affected by several variables. Determining the development of the true incidence is critical to the establishment of proper treatment of these patients. Objective To evaluate… read more here.
Keywords: incidence; detection rate; major chd; chd ... See more keywords
Joint Associations of APOC3 and LDL-C-Lowering Variants With the Risk of Coronary Heart Disease.
Sign Up to like & getrecommendations! Published in 2025 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2025.0195
Abstract: Importance Despite substantial progress in low-density lipoprotein cholesterol (LDL-C)-lowering strategies, residual cardiovascular risk remains. Apolipoprotein C3 (APOC3) has emerged as a novel target for lowering triglycerides. Multiple clinical trials of small-interfering RNA therapeutics targeting APOC3… read more here.
Keywords: risk; chd; apoc3; pcsk9 ... See more keywords
Associations between coronary heart disease and risk of cognitive impairment: A meta‐analysis
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DOI: 10.1002/brb3.2108
Abstract: Several studies have demonstrated that coronary heart disease (CHD) is a high risk factor for cognitive impairment, whereas other studies showed that there was no association between cognitive impairment and CHD. The relationship between CHD… read more here.
Keywords: risk; heart disease; cognitive impairment; impairment ... See more keywords
Molecular sex identification of Malaysian White‐Nest Swiftlet (Aerodramus fuciphagus Thunberg, 1812)
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DOI: 10.1002/ece3.6699
Abstract: Abstract The difficulty in differentiating the sex of monomorphic bird species has made molecular sexing an important tool in addressing this problem. This method uses noninvasively collected materials such as feathers and may be advantageous… read more here.
Keywords: chd gene; sex; chd; chd chd ... See more keywords
Sphingomyelin and progression of renal and coronary heart disease in individuals with type 1 diabetes
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DOI: 10.1007/s00125-020-05201-9
Abstract: Lipid abnormalities are associated with diabetic kidney disease and CHD, although their exact role has not yet been fully explained. Sphingomyelin, the predominant sphingolipid in humans, is crucial for intact glomerular and endothelial function. Therefore,… read more here.
Keywords: disease; type diabetes; chd; sphingomyelin ... See more keywords
Cardiovascular health in early adulthood predicts the development of coronary heart disease in individuals with type 1 diabetes: 25 year follow-up from the Pittsburgh Epidemiology of Diabetes Complications study
Sign Up to like & getrecommendations! Published in 2020 at "Diabetologia"
DOI: 10.1007/s00125-020-05328-9
Abstract: Type 1 diabetes increases CHD risk. We examined the use of the American Heart Association’s cardiovascular health metrics (blood pressure, total cholesterol, glucose/HbA1c, BMI, physical activity, diet, smoking) to predict incidence of CHD among individuals… read more here.
Keywords: heart; cardiovascular health; type diabetes; epidemiology ... See more keywords
Risk of Respiratory Syncytial Virus Hospitalization in the First and Second Years of Life in Pediatric Patients with Congenital Heart Disease
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DOI: 10.1007/s00246-017-1634-5
Abstract: Previous data have demonstrated that children aged \24 months with hemodynamically significant congenital heart disease (HS-CHD) are at elevated risk for severe respiratory syncytial virus (RSV) disease. However, based upon the more recent assertion that… read more here.
Keywords: risk; children aged; mortality; aged months ... See more keywords
A Genetic Variant in FIGN Gene Reduces the Risk of Congenital Heart Disease in Han Chinese Populations
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DOI: 10.1007/s00246-017-1636-3
Abstract: Congenital heart disease (CHD) is one of the most common birth anomalies worldwide. Folate deficiency is an independent risk factor for CHD. Genome-wide association studies (GWAS) revealed that human folate level could be significantly influenced… read more here.
Keywords: fign gene; congenital heart; chd; fign ... See more keywords
Scientific Abstracts 8th Phoenix Fetal Cardiology Symposium October 27–31, 2017
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DOI: 10.1007/s00246-017-1774-7
Abstract: Scientific Abstracts 8th Phoenix Fetal Cardiology Symposium October 27–31, 2017 Sponsored by Phoenix Children’s Hospital, Phoenix, AZ Springer Science+Business Media, LLC, part of Springer Nature 2017 Normal Reference Ranges for Cardiac Valve CrossSectional Areas in… read more here.
Keywords: cross sectional; cardiology; sectional areas; valve cross ... See more keywords
A Novel MEF2C Loss-of-Function Mutation Associated with Congenital Double Outlet Right Ventricle
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DOI: 10.1007/s00246-018-1822-y
Abstract: Congenital heart defect (CHD) represents the most prevalent birth defect, and accounts for substantial morbidity and mortality in humans. Aggregating evidence demonstrates the genetic basis for CHD. However, CHD is a heterogeneous disease, and the… read more here.
Keywords: outlet right; double outlet; congenital double; chd ... See more keywords