Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Cardiology"
DOI: 10.1001/jamacardio.2018.1470
Abstract: Importance Human genetic studies have indicated that plasma lipoprotein(a) (Lp[a]) is causally associated with the risk of coronary heart disease (CHD), but randomized trials of several therapies that reduce Lp(a) levels by 25% to 35%… read more here.
Keywords: risk; change; chd risk; level ... See more keywords
Co-Exposure to Bisphenols, Parabens, and Antimicrobials and Association with Coronary Heart Disease: Oxidative Stress as a Potential Mediating Factor?
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.2c06488
Abstract: Coronary heart disease (CHD) is the leading cause of global morbidity, but the effect of plasticizers and antimicrobial additives on CHD is unknown. Here, we conducted a case-control study to investigate the mediating role of… read more here.
Keywords: exposure; coronary heart; oxidative stress; chd risk ... See more keywords
Associations Between Midlife but not Late-Life, Elevated Coronary Heart Disease Risk and Lower Cognitive Performance: Results From the Framingham Offspring Study.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of epidemiology"
DOI: 10.1093/aje/kwz210
Abstract: It is unclear how coronary heart disease (CHD) risk across the adult lifespan affects latelife cognition. We estimated associations of mid-life and late-life elevated CHD risk with cognitive trajectories (general cognitive performance, processing speed/executive function,… read more here.
Keywords: risk; life; chd risk; cognitive performance ... See more keywords
Sex Hormone-Binding Globulin and Risk of Coronary Heart Disease in Men and Women.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical chemistry"
DOI: 10.1093/clinchem/hvac209
Abstract: BACKGROUND The role of sex hormone-binding globulin (SHBG) levels in clinical risk stratification and intervention for coronary heart disease (CHD) remains uncertain. We aimed to examine whether circulating levels of SHBG are predictive of CHD… read more here.
Keywords: shbg; chd risk; men women; sex hormone ... See more keywords
The Effect of Thyroid Dysfunction on the Cardiovascular Risk of Type 2 Diabetes Mellitus Patients in Ghana
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Diabetes Research"
DOI: 10.1155/2018/4783093
Abstract: Background Thyroid dysfunction is known to exaggerate the coronary heart disease (CHD) risk associated with type 2 diabetes mellitus (T2DM) among whites. The effect is yet to be studied among African populations. Methods This is… read more here.
Keywords: thyroid dysfunction; type diabetes; risk; chd risk ... See more keywords
Association of Sirtuin 1 Gene Polymorphisms with the Risk of Coronary Heart Disease in Chinese Han Patients with Type 2 Diabetes Mellitus
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Diabetes Research"
DOI: 10.1155/2022/8494502
Abstract: Aims To explore the associations between polymorphisms in SIRT1 and coronary heart disease (CHD) risk in Chinese Han patients with type 2 diabetes (T2D). Methods This case-controlled study enrolled 492 patients with T2D: 297 with… read more here.
Keywords: coronary heart; chd risk; chinese han; risk ... See more keywords
Missense Variant rs28362680 in BTNL2 Reduces Risk of Coronary Heart Disease
Sign Up to like & getrecommendations! Published in 2022 at "Pharmacogenomics and Personalized Medicine"
DOI: 10.2147/pgpm.s353085
Abstract: Background The pathological basis of coronary heart disease (CHD) is atherosclerosis. BTNL2 can inhibit the activation of T cells. We aimed to explore the association between BTNL2 genetic variants and CHD risk in the southern… read more here.
Keywords: rs28362680; missense; chd risk; analysis ... See more keywords
Cardiovascular risk in perimenopausal women.
Sign Up to like & getrecommendations! Published in 2018 at "Current vascular pharmacology"
DOI: 10.2174/1570161116666181002145340
Abstract: Cardiovascular disease, and particularly coronary heart disease (CHD), has a low incidence in premenopausal women. Loss of ovarian hormones during the perimenopause and menopause leads to a sharp increase in incidence. Although most CHD risk… read more here.
Keywords: risk; chd risk; risk factors; cardiovascular risk ... See more keywords
Small Dense LDL: Scientific Background, Clinical Relevance, and Recent Evidence Still a Risk Even with ‘Normal’ LDL-C Levels
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10040829
Abstract: Residual cardiovascular disease event risk, following statin use and low-density lipoprotein cholesterol (LDL-C) reduction, remains an important and common medical conundrum. Identifying patients with significant residual risk, despite statin drug use, is an unmet clinical… read more here.
Keywords: chd risk; clinical relevance; risk; evidence ... See more keywords
Serum Alanine Aminotransferase Level as a Risk Factor for Coronary Heart Disease Prediction in Koreans: Analysis of the Korea National Health and Nutrition Examination Survey (V-1, 2010 and V-2, 2011)
Sign Up to like & getrecommendations! Published in 2019 at "Korean Journal of Family Medicine"
DOI: 10.4082/kjfm.17.0068
Abstract: Background The blood level of alanine aminotransferase (ALT) is associated with increased coronary heart disease (CHD) risk. However, its use as an independent factor for CHD risk prediction remains unclear in Asian populations. The purpose… read more here.
Keywords: risk; chd risk; alanine aminotransferase; serum ... See more keywords