Oligodendrocyte precursor survival and differentiation requires chromatin remodeling by Chd7 and Chd8
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DOI: 10.1073/pnas.1802620115
Abstract: Significance Oligodendrocyte precursor cells (OPCs) constitute the main proliferative cells in the adult brain and deregulation of OPC proliferation-differentiation balance results in either glioma formation or defective (re)myelination. Mutations in chromatin remodelers CHD7 and CHD8… read more here.
Keywords: chromatin; oligodendrocyte precursor; differentiation; chd7 chd8 ... See more keywords