Articles with "chd8 genomic" as a keyword



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Common CHD8 Genomic Targets Contrast With Model-Specific Transcriptional Impacts of CHD8 Haploinsufficiency

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Published in 2019 at "Frontiers in Molecular Neuroscience"

DOI: 10.3389/fnmol.2018.00481

Abstract: The packaging of DNA into chromatin determines the transcriptional potential of cells and is central to eukaryotic gene regulation. Case sequencing studies have revealed mutations to proteins that regulate chromatin state, known as chromatin remodeling… read more here.

Keywords: transcriptional impacts; chd8 genomic; chromatin; chd8 ... See more keywords