Chebulinic Acid Suppresses Adipogenesis in 3T3-L1 Preadipocytes by Inhibiting PPP1CB Activity
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23020865
Abstract: Depletion of protein phosphatase-1 catalytic subunit beta (PPP1CB), a serine/threonine protein phosphatase and potent adipogenic activator, suppresses the differentiation of 3T3-L1 preadipocytes into mature adipocytes. Therefore, PPP1CB is considered as a potential therapeutic target for… read more here.
Keywords: acid suppresses; 3t3 preadipocytes; ppp1cb; adipogenesis 3t3 ... See more keywords
Gastric ulcer healing by chebulinic acid solid dispersion-loaded gastroretentive raft systems: preclinical evidence.
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic delivery"
DOI: 10.4155/tde-2021-0062
Abstract: Background: Chebulinic acid (CA), a component in Terminalia chebula, exhibits antiulcer activity, but has poor aqueous solubility. Raft-forming systems incorporating solid dispersions (SDs) of CA, were developed to overcome its poor biopharmaceutical properties and to… read more here.
Keywords: raft; ulcer healing; gastric ulcer; raft systems ... See more keywords