Strong founder effect for BRCA1 c.3629_3630delAG pathogenic variant in Chechen patients with breast or ovarian cancer
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DOI: 10.1002/cam4.5159
Abstract: Coding sequences of BRCA1, BRCA2, ATM, TP53, and PALB2 genes were analyzed in 68 consecutive Chechen patients with highâgrade serous ovarian cancer (HGSOC). Pathogenic BRCA1/2 variants were identified in 15 (22%) out of 68 HGSOC… read more here.
Keywords: chechen patients; brca1; brca1 3629; ovarian cancer ... See more keywords