Checkerboard: a Bayesian efficacy and toxicity interval design for phase I/II dose-finding trials
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DOI: 10.1080/10543406.2020.1815033
Abstract: ABSTRACT The rise of targeted therapy and immunotherapy has challenged the conventional more-is-better phase I trial design paradigm that focuses on finding the MTD. In this article, we propose a novel model-assisted phase I/II design,… read more here.
Keywords: phase; efficacy; toxicity efficacy; checkerboard design ... See more keywords