Sarcoidosis related to checkpoint and BRAF/MEK inhibitors in melanoma.
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DOI: 10.1016/j.autrev.2020.102587
Abstract: Therapy for advanced melanoma has deeply changed in the last decade with the introduction of checkpoint and BRAF/MEK inhibitors. Granulomatous reactions have been reported related to these drugs. We performed a systematic review of all… read more here.
Keywords: braf mek; checkpoint braf; mek inhibitors; sarcoidosis ... See more keywords
The association between immune checkpoint or BRAF/MEK inhibitor therapy and uveitis in patients with advanced cutaneous melanoma.
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DOI: 10.1016/j.ejca.2020.11.027
Abstract: BACKGROUND Treatment with immune checkpoint and BRAF/MEK inhibitors has significantly improved the survival of patients with advanced cutaneous melanoma and other metastatic malignancies. Therapy-related uveitis is a rare ocular adverse event, which may potentially lead… read more here.
Keywords: immune checkpoint; braf mek; checkpoint braf;
Impact of immune checkpoint and BRAF inhibitors on the incidence of second primary malignancies (SPM) in melanoma.
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DOI: 10.1200/jco.2020.38.15_suppl.12061
Abstract: 12061Background: Prior studies have shown an increased risk of SPM in melanoma, however there is limited data on the incidence of SPM following the 2011 approvals of immune checkpoint (ipilimumab) ... read more here.
Keywords: immune checkpoint; checkpoint braf; spm melanoma; impact immune ... See more keywords