Checkpoint protein expression in the tumor microenvironment defines the outcome of classical Hodgkin lymphoma patients
Sign Up to like & getrecommendations! Published in 2021 at "Blood Advances"
DOI: 10.1182/bloodadvances.2021006189
Abstract: Key Points Composition of the cHL microenvironment is heterogeneous and differs in the proportions of T cells and macrophages. High T cell and macrophage-mediated checkpoint protein expression in the cHL microenvironment associates with inferior OS. read more here.
Keywords: expression tumor; tumor microenvironment; protein expression; checkpoint protein ... See more keywords
B7-H3 immune checkpoint protein in human cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Current medicinal chemistry"
DOI: 10.2174/0929867326666190517115515
Abstract: B7-H3 belongs to the B7 family of immune checkpoint proteins, which are important regulators of the adaptive immune response and emerging key players in human cancer. B7-H3 is a transmembrane protein expressed on the surface… read more here.
Keywords: cancer immune; immune checkpoint; checkpoint protein; human cancer ... See more keywords
A Systematic RNAi Screen Reveals a Novel Role of a Spindle Assembly Checkpoint Protein BuGZ in Synaptic Transmission in C. elegans
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2017.00141
Abstract: Synaptic vesicles (SV) store various neurotransmitters that are released at the synapse. The molecular mechanisms of biogenesis, exocytosis, and endocytosis for SV, however, remain largely elusive. In this study, using Complex Object Parametric Analysis and… read more here.
Keywords: spindle assembly; checkpoint protein; screen; protein bugz ... See more keywords