Association of TIM-3 checkpoint receptor expression on T cells with treatment-free remission in chronic myeloid leukemia
Sign Up to like & getrecommendations! Published in 2023 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022008854
Abstract: Key Points • TIM-3 is the only immune-checkpoint receptor consistently overexpressed in patients with CML who relapse after TKI cessation.• Overexpression of TIM-3 provides a rationale to test TIM-3 inhibitors to modify treatment-free remission outcomes. read more here.
Keywords: tim; checkpoint receptor; treatment free; free remission ... See more keywords
Expression of the immune checkpoint receptor TIGIT in seminoma
Sign Up to like & getrecommendations! Published in 2019 at "Oncology Letters"
DOI: 10.3892/ol.2019.10428
Abstract: A characteristic feature of testicular seminoma is the abundance of immune cells in the tumor microenvironment, raising the possibility that immune checkpoint inhibitors may serve as a therapeutic option in these types of tumors. T… read more here.
Keywords: immune checkpoint; tigit; checkpoint receptor; checkpoint ... See more keywords