Immune checkpoints and cancer in the immunogenomics era.
Sign Up to like & getrecommendations! Published in 2019 at "Briefings in functional genomics"
DOI: 10.1093/bfgp/ely027
Abstract: Immune checkpoints have been the subject of a wave of new studies. Among these checkpoints are tytotoxic T-lymphocyte-associated antigen 4, checkpoints programmed death-1 and programmed death-ligand 1; their blockades have been approved by the Food… read more here.
Keywords: immune checkpoint; immunogenomics era; cancer immunogenomics; therapy ... See more keywords
Next generation immune-checkpoints for cancer therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of thoracic disease"
DOI: 10.21037/jtd.2018.02.79
Abstract: The discovery and clinical application of immune-checkpoint inhibitors has dramatically improved the treatments, outcomes and therapeutic concepts in multiple tumor settings. This breakthrough was mainly based on monoclonal antibodies blocking the inhibitory molecule CTLA-4 and… read more here.
Keywords: next generation; immune checkpoints; checkpoints cancer; generation immune ... See more keywords
Diversity of immune checkpoints in cancer immunotherapy
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1121285
Abstract: Finding effective treatments for cancer remains a challenge. Recent studies have found that the mechanisms of tumor evasion are becoming increasingly diverse, including abnormal expression of immune checkpoint molecules on different immune cells, in particular… read more here.
Keywords: cancer; checkpoints cancer; checkpoint; immune checkpoints ... See more keywords