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Published in 2018 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2018.00464
Abstract: Targeting the Immune Checkpoint molecules (ICs; CTLA-4, PD-1, PD-L1/2, and others) which provide inhibitory signals to T cells, dramatically improves survival in hard-to-treat tumors. The establishment of an immunosuppressive environment prevents endogenous immune response in…
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Keywords:
checkpoints innovative;
therapies glioblastoma;
innovative therapies;
immune checkpoints ... See more keywords