CHEK1 variant is a risk factor for premature ovarian insufficiency by mis- regulating metabolism and inflammation-related genes
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DOI: 10.1186/s40246-025-00774-1
Abstract: Premature ovarian insufficiency (POI) is affecting approximately 1% of females and increasingly contributing to female infertility. The etiology of POI is heterogeneous. CHEK1, a critical component of the DNA damage and replication stress response, has… read more here.
Keywords: premature ovarian; chek1 variant; ovarian insufficiency; metabolism inflammation ... See more keywords