Incidence of the CHEK2 Germline Mutation and Its Impact on Clinicopathological Features, Treatment Responses, and Disease Course in Patients with Papillary Thyroid Carcinoma
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DOI: 10.3390/cancers13030470
Abstract: Simple Summary The aim of our study was to evaluate whether the CHEK2 mutation was a predictor of poorer clinical course in patients with papillary thyroid cancer. The study included 1547 patients from a single… read more here.
Keywords: mutation; papillary thyroid; treatment; chek2 ... See more keywords
CHEK2 Alterations in Pediatric Malignancy: A Single-Institution Experience
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DOI: 10.3390/cancers15061649
Abstract: Simple Summary Pediatric malignancies rarely occur, with 12,000–15,000 cases per year in the United States. Approximately 10% of pediatric cancers are thought to be secondary to germline alterations in cancer-predisposing genes based on numerous germline… read more here.
Keywords: oncology; germline alterations; single institution; institution experience ... See more keywords