The CHK2 kinase is recurrently mutated and functionally impaired in the germline of pediatric cancer patients
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DOI: 10.1002/ijc.34390
Abstract: Predisposing CHEK2 germline variants are associated with various adult‐type malignancies, whereas their impact on cancer susceptibility in childhood cancer is unclear. To understand the frequency of germline variants in the CHEK2 gene and their impact… read more here.
Keywords: pediatric cancer; germline; cancer patients; chek2 variants ... See more keywords