Designing a new multifunctional peptide for metal chelation and Aβ inhibition.
Sign Up to like & getrecommendations! Published in 2018 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2018.06.004
Abstract: According to the Amyloid hypothesis, as the foremost scientific explanation for Alzheimer Disease (AD), the neuropathology of AD is related to toxic fragments of amyloid beta (Aβ) protein. Based on this hypothesis, an attractive therapeutic… read more here.
Keywords: chelation; new multifunctional; multifunctional peptide; metal ... See more keywords
Impacts of lead exposure and chelation therapy on bone metabolism during different developmental stages of rats.
Sign Up to like & getrecommendations! Published in 2019 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2019.109441
Abstract: OBJECTIVE To explore the impacts of Pb exposure and the dimercaptosuccinic acid (DMSA) chelation therapy on bone metabolisms in young rats of different ages, as well as the potential mechanisms. METHOD Young rats were exposed… read more here.
Keywords: chelation; dmsa chelation; exposure; bone ... See more keywords
Chelation, formulation, encapsulation, retention, and in vivo biodistribution of hydrophobic nanoparticles labelled with 57Co‐porphyrin: Oleylamine ensures stable chelation of cobalt in nanoparticles that accumulate in tumors
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2018.09.027
Abstract: Background and motivation: While small molecules can be used in cancer diagnosis there is a need for imageable diagnostic NanoParticles (NPs) that act as surrogates for the therapeutic NPs. Many NPs are composed of hydrophobic… read more here.
Keywords: biodistribution; chelation; cobalt; oep ... See more keywords
Chelation mode impact of copper(II)-aminosilane complexes immobilized onto graphene oxide as an oxidative catalyst
Sign Up to like & getrecommendations! Published in 2017 at "Journal of environmental chemical engineering"
DOI: 10.1016/j.jece.2017.05.020
Abstract: Abstract Copper (II) was chelated with mono-, di- and tri-aminosilane functionalized graphene oxide (GO) and denoted as CAT1, CAT2, and CAT3. GO/Cu(II)-aminosilane complexes were characterized by Fourier transform infrared, X-ray diffraction, energy dispersive X-ray, thermogravimetric,… read more here.
Keywords: graphene oxide; chelation; mode; aminosilane complexes ... See more keywords
The Effect of Heating to Intracanal Temperature on the Stability of Sodium Hypochlorite Admixed with Etidronate or EDTA for Continuous Chelation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Endodontics"
DOI: 10.1016/j.joen.2018.09.014
Abstract: Introduction Tetrasodium etidronate (Na4 etidronate) and tetrasodium EDTA (Na4 EDTA) are chelators that can combine with sodium hypochlorite (NaOCl) as a 1‐mix endodontic irrigant in a process called continuous chelation. The therapeutic window of these… read more here.
Keywords: continuous chelation; chelation; temperature; edta ... See more keywords
Protocatechuic acid-metal-nicotine complexation study for chelation of smoking-related poisoning
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2020.113428
Abstract: Abstract Nephropathy in tobacco smoker is postulated to be caused by nicotine (Nic) and catalyzed by various heavy metals (M(II) = Ni(II), Pb(II), and Cd(II)) contained in commercial cigarettes. Once absorbed through the lungs, these compounds will… read more here.
Keywords: chelation; nic heavy; study; protocatechuic acid ... See more keywords
Étude de l’hémosidérose post-transfusionnelle et de la chélation chez les patients avec syndrome myélodysplasique (SMD) transfusés en 2017 au CHANGE
Sign Up to like & getrecommendations! Published in 2018 at "Transfusion Clinique et Biologique"
DOI: 10.1016/j.tracli.2018.08.027
Abstract: L’hemosiderose post-transfusionnelle reste sous declaree en France, 39 FEIR en 2016, 0,58 % des FEIR rapport ANSM aucune declaration au CHANGE. Dans l’etude SFVTT 2014, sur l’hemosiderose post-transfusionnelle, les SMD representent 32 % des patients. Chez les patients… read more here.
Keywords: post transfusionnelle; chelation; patients smd; chez les ... See more keywords
Advancing Chelation Strategies for Large Metal Ions for Nuclear Medicine Applications.
Sign Up to like & getrecommendations! Published in 2022 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.2c00003
Abstract: ConspectusNuclear medicine leverages radioisotopes of a wide range of elements, a significant portion of which are metals, for the diagnosis and treatment of disease. To optimally use radioisotopes of the metal ions, or radiometals, for… read more here.
Keywords: chemistry; medicine; nuclear medicine; chelation ... See more keywords
Chelation-Controlled Additions to Chiral α- and β-Silyloxy, α-Halo, and β-Vinyl Carbonyl Compounds.
Sign Up to like & getrecommendations! Published in 2017 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.7b00319
Abstract: The science and art of preventing and managing disease and prolonging life is dependent on advances in medicine, biology, and biochemistry. Many of these advances will involve interactions of small molecules with biological entities. As… read more here.
Keywords: chelation controlled; chelation; chiral silyloxy; controlled additions ... See more keywords
Instability at the Electrode/Electrolyte Interface Induced by Hard Cation Chelation and Nucleophilic Attack
Sign Up to like & getrecommendations! Published in 2017 at "Chemistry of Materials"
DOI: 10.1021/acs.chemmater.7b03404
Abstract: Electrochemistry is necessarily a science of interfacial processes, and understanding electrode/electrolyte interfaces is essential to controlling electrochemical performance and stability. Undesirable interfacial interactions hinder discovery and development of rational materials combinations. By example, we examine… read more here.
Keywords: chelation; instability; nucleophilic attack; chemistry ... See more keywords
A Third Generation Potentially Bifunctional Trithiol Chelate, Its nat,1XXSb(III) Complex, and Selective Chelation of Radioantimony (119Sb) from Its Sn Target.
Sign Up to like & getrecommendations! Published in 2021 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.1c01690
Abstract: The therapeutic potential of the Meitner-Auger- and conversion-electron emitting radionuclide 119Sb remains unexplored because of the difficulty of incorporating it into biologically targeted compounds. To address this challenge, we report the development of 119Sb production… read more here.
Keywords: chelation; trithiol chelate; trithiol; third generation ... See more keywords