Optic neuropathy in iron overload and iron chelation therapy
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26511
Abstract: States of systemic iron overaload, such as hereditary hemosiderosis and iron overload secondary to transfusion dependence, are known to be associated with optic neuropathy. 1 – 3 Similarly, several studies have shown the treatment of… read more here.
Keywords: chelation therapy; optic neuropathy; iron overload; iron ... See more keywords
Impacts of lead exposure and chelation therapy on bone metabolism during different developmental stages of rats.
Sign Up to like & getrecommendations! Published in 2019 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2019.109441
Abstract: OBJECTIVE To explore the impacts of Pb exposure and the dimercaptosuccinic acid (DMSA) chelation therapy on bone metabolisms in young rats of different ages, as well as the potential mechanisms. METHOD Young rats were exposed… read more here.
Keywords: chelation; dmsa chelation; exposure; bone ... See more keywords
Adherence to Iron Chelation Therapy among Adults with Thalassemia: A Systematic Review
Sign Up to like & getrecommendations! Published in 2022 at "Hemoglobin"
DOI: 10.1080/03630269.2022.2072320
Abstract: Abstract Iron chelation therapy (ICT) is essential to prevent complications of iron overload in patients with transfusion-dependent thalassemia. However, the role that adherence to ICT plays in health-related outcomes is less well known. Our objectives… read more here.
Keywords: chelation therapy; ict adherence; adherence; iron chelation ... See more keywords
Excretion of Pu-238 during Long-term Chelation Therapy by Repeated DTPA Inhalation
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DOI: 10.1097/hp.0000000000001584
Abstract: Abstract An individual underwent an extensive diethylenetriaminepentaacetate (DTPA) chelation therapy that started several months after plutonium incorporation, most likely by inhalation of a soluble compound. After receiving multiple intravenous infusions of DTPA, the patient continued… read more here.
Keywords: chelation; chelation therapy; dtpa inhalation; therapy ... See more keywords
The impact of iron chelation therapy on patients with lower/intermediate IPSS MDS and the prognostic role of elevated serum ferritin in patients with MDS and AML
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DOI: 10.1097/md.0000000000017406
Abstract: Supplemental Digital Content is available in the text read more here.
Keywords: therapy patients; chelation therapy; lower intermediate; iron chelation ... See more keywords
Characterisation of individual ferritin response in patients receiving chelation therapy
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.15290
Abstract: To develop a drug–disease model describing iron overload and its effect on ferritin response in patients affected by transfusion‐dependent haemoglobinopathies and investigate the contribution of interindividual differences in demographic and clinical factors on chelation therapy… read more here.
Keywords: individual ferritin; characterisation individual; chelation therapy; response patients ... See more keywords
Clinical view versus guideline adherence in ferritin monitoring and initiating iron chelation therapy in patients with myelodysplastic syndromes
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Haematology"
DOI: 10.1111/ejh.13865
Abstract: In patients with myelodysplastic syndromes (MDS) with >20 transfusions and ferritin levels >1000 μg/L, international guidelines recommend iron chelation therapy (ICT). The study's objective was to determine guideline adherence and the intensity of ferritin monitoring in… read more here.
Keywords: ferritin; iron chelation; myelodysplastic syndromes; guideline adherence ... See more keywords
Iron chelation therapy
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Haematology"
DOI: 10.1111/ejh.13935
Abstract: Iron overload is a pathological condition resulting from a congenital impairment of its regulation, increased intestinal iron absorption secondary to bone marrow erythroid hyperplasia, or a chronic transfusional regimen. In normal conditions, intracellular and systemic… read more here.
Keywords: chelation therapy; iron; iron overload; iron chelation ... See more keywords
Treatment Patterns and Costs of Transfusion and Chelation in Commercially-Insured and Medicaid Patients with Transfusion-Dependent β-Thalassemia
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DOI: 10.1182/blood.v130.suppl_1.5635.5635
Abstract: BACKGROUND: β-thalassemia is a potentially life-threatening, hereditary blood disorder characterized by ineffective erythropoiesis and peripheral hemolysis, leading to profound anemia and iron avidity. It is estimated to affect approximately 15,000 people in the U.S. and… read more here.
Keywords: chelation; treatment; rbc transfusions; transfusion ... See more keywords
Lead Levels in the Eggs of a Chicken With Lead Toxicosis
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DOI: 10.1647/2017-313
Abstract: Abstract A 1.5-year-old Polish hen was presented with a history of watery droppings and poor vent tone. Results of diagnostic tests revealed blood lead at levels considered to be toxic. Chelation therapy was started with… read more here.
Keywords: lead levels; lead; end chelation; chelation therapy ... See more keywords
Effect of drug use calendar on adherence to iron chelation therapy in young thalassemia patients
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DOI: 10.18549/pharmpract.2022.1.2570
Abstract: Background: Regular blood transfusions in thalassemia patients can lead to severe complications and iron chelation therapy is required as a treatment. Thalassemia is common in Thailand and the drugs used in iron chelation therapy are… read more here.
Keywords: calendar; adherence; iron chelation; thalassemia patients ... See more keywords