Binding mode exploration of LuxR-thiazolidinedione analogues, e-pharmacophore-based virtual screening in the designing of LuxR inhibitors and its biological evaluation
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DOI: 10.1080/07391102.2016.1166455
Abstract: Master quorum sensing (QS) regulator LuxR of Vibrio harveyi is a unique member of the TetR protein superfamily. Recent studies have demonstrated the contribution of thiazolidinedione analogues in blocking QS by decreasing the DNA-binding ability… read more here.
Keywords: chembridge 5343641; thiazolidinedione analogues; mode exploration; binding mode ... See more keywords