Association of Chemerin Plasma Concentration With Risk of Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2019.0896
Abstract: Key Points Question Is there an association between peripheral concentrations of the proinflammatory biomarker chemerin and incident colorectal cancer? Findings In this case-cohort study that included 221 incident colorectal cancer cases and 2329 cancer-free participants,… read more here.
Keywords: risk colorectal; colorectal cancer; association; cancer ... See more keywords
Adipokine Chemerin Bridges Metabolic Dyslipidemia and Alveolar Bone Loss in Mice
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3072
Abstract: Chemerin is an adipokine that regulates adipogenesis and metabolic functions of mature adipocytes mainly through the activation of chemokine‐like receptor 1 (CMKLR1). Elevated levels of chemerin have been found in individuals with obesity, type 2… read more here.
Keywords: bone; adipokine; mice; bone loss ... See more keywords
Chemerin induces lipolysis through ERK1/2 pathway in intramuscular mature adipocytes of dairy bull calves
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27506
Abstract: The adipokine Chemerin has been reported to regulate differentiation and metabolism of adipocytes, but the mechanism underlying lipolysis is still largely unknown. The purpose of this study was to explore whether ERK1/2 pathway is involved… read more here.
Keywords: erk1 pathway; mature adipocytes; dairy bull; intramuscular mature ... See more keywords
Chemerin induced by Treponema pallidum predicted membrane protein Tp0965 mediates the activation of endothelial cell via MAPK signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29269
Abstract: Chemerin, a chemoattractant protein, is involved in endothelial dysfunction and vascular inflammation in pathological conditions. In a recent study, we observed the upregulation of chemerin in endothelial cells following in vitro treatment with Treponema pallidum.… read more here.
Keywords: protein; tp0965; signaling pathway; endothelial cells ... See more keywords
Chemerin located in bone marrow promotes osteogenic differentiation and bone formation via Akt/Gsk3β/β‐catenin axis in mice
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30290
Abstract: Chemerin, a secreted protein mainly produced by adipocytes and hepatocytes, plays a variety of roles in endocrine or paracrine signaling. As reported in human epidemiology, chemerin was correlated with osteoporosis. And the previous in vitro… read more here.
Keywords: catenin; bone; osteogenic differentiation; mice ... See more keywords
Chemerin/ChemR23 regulates cementoblast function and tooth resorption in mice via inflammatory factors.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of periodontology"
DOI: 10.1002/jper.20-0675
Abstract: BACKGROUND Periodontitis and orthodontic treatment can lead to inflammatory root resorption (IRR) through an unclear mechanism. Chemerin, a novel chemoattractant protein, is closely associated with inflammation, affects osteoblast and osteoclast differentiation, and may play a… read more here.
Keywords: chemr23; chemerin chemr23; expression; cementoblast function ... See more keywords
CDK4/6 inhibitor protects chemerin‐induced human granulosa‐lutein cells from apoptosis by inhibiting the p53/p21 waf pathway
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23241
Abstract: Dysregulation of the cell cycle is common in human tumorigenesis. Therefore, CDK4/6 inhibitors targeting the cell cycle have been developed, and their antiapoptotic effects have been highly correlated with potential clinical therapies. The aim of… read more here.
Keywords: cdk4 inhibitor; hgl cells; chemerin induced; granulosa lutein ... See more keywords
Impact of chemerin, lipid profile, and insulin resistance on disease parameters in patients with multiple sclerosis
Sign Up to like & getrecommendations! Published in 2020 at "Neurological Sciences"
DOI: 10.1007/s10072-020-04847-y
Abstract: Plasma chemerin, which has chemotactic and adipogenic functions, is increased in several inflammatory diseases. However, its relationship with multiple sclerosis (MS) has not been explored yet. In this study, we aimed to determine chemerin levels… read more here.
Keywords: insulin; serum chemerin; chemerin levels; multiple sclerosis ... See more keywords
Hepatocyte expressed chemerin-156 does not protect from experimental non-alcoholic steatohepatitis.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-022-04430-3
Abstract: Non-alcoholic steatohepatitis (NASH) is a rapidly growing liver disease. The chemoattractant chemerin is abundant in hepatocytes, and hepatocyte expressed prochemerin protected from NASH. Prochemerin is inactive and different active isoforms have been described. Here, the… read more here.
Keywords: hepatocyte expressed; chemerin; alcoholic steatohepatitis; non alcoholic ... See more keywords
Preoperative Chemerin Level Is Predictive of Inflammatory Status 1 Year After Bariatric Surgery
Sign Up to like & getrecommendations! Published in 2020 at "Obesity Surgery"
DOI: 10.1007/s11695-020-04584-3
Abstract: Background Obesity is associated with chronic low-grade inflammation, which has been linked to increased morbidity. However, inflammation variably and unpredictably improves after bariatric surgery. This study aimed at (1) evaluating the relationship between amplitude of… read more here.
Keywords: surgery; bariatric surgery; weight loss; inflammatory ... See more keywords
Chemerin-9 stimulates migration in rat cardiac fibroblasts in vitro.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2021.174566
Abstract: Since chemerin is an adipocytokine whose concentration in blood increases in the subjects with various cardiac diseases, chemerin may be involved in pathogenesis of cardiac diseases. In the present study, we examined the effects of… read more here.
Keywords: stimulates migration; cardiac diseases; chemerin stimulates; cardiac fibroblasts ... See more keywords