A Fluorescent Reverse-Transcription Assay to Detect Chemical Adducts on RNA.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00270
Abstract: Herein, we detail a novel reverse-transcription (RT) assay to directly detect chemical adducts on RNA. We optimize a fluorescence quenching assay to detect RT polymerization and employ our approach to detect N1-alkylation of inosine, an… read more here.
Keywords: assay detect; adducts rna; detect chemical; transcription assay ... See more keywords
Tuning curved DNA origami structures through mechanical design and chemical adducts
Sign Up to like & getrecommendations! Published in 2022 at "Nanotechnology"
DOI: 10.1088/1361-6528/ac7d62
Abstract: The bending and twisting of DNA origami structures are important features for controlling the physical properties of DNA nanodevices. It has not been fully explored yet how to finely tune the bending and twisting of… read more here.
Keywords: origami structures; tuning curved; curved dna; chemical adducts ... See more keywords
Broad responses to chemical adducts shape the natural antibody repertoire in early infancy
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.ade8872
Abstract: Natural antibodies are an integral part of innate humoral immunity yet their development and polyreactive nature are still enigmatic. Here, we show that characteristic monoclonal natural antibodies recognize common chemical moieties or adducts, supporting the… read more here.
Keywords: natural antibody; adducts shape; shape natural; chemical adducts ... See more keywords