2nd PSL Chemical Biology Symposium (2019): At the Crossroads of Chemistry and Biology
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DOI: 10.1002/cbic.201900092
Abstract: Chemical Biology is the science of designing chemical tools to dissect and manipulate biology at different scales. It provides the fertile ground from which to address important problems of our society, such as human health… read more here.
Keywords: 2nd psl; chemical biology; psl chemical; chemistry ... See more keywords
Time to Get Turned on by Chemical Biology
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DOI: 10.1002/cbic.202000497
Abstract: The pressing need for innovation in drug discovery is spurring the emergence of drugs that turn on protein function, as opposed to shutting activity down. Several pharmacophores usher protein target gain‐of‐function, for instance: PROTACs promote… read more here.
Keywords: chemical biology; target; time get; biology ... See more keywords
Navigating the Biological‐Material Interface with the Guide of Chemical Biology
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DOI: 10.1002/cbic.202000529
Abstract: Research at the biological‐material interface often has translation in mind, with applications in medical implants, drug delivery, and regenerative medicine. While the clinical impact of this research is undeniable, a clearer picture of the in… read more here.
Keywords: material interface; biology; chemical biology; biological material ... See more keywords
Chemical Biology Tools To Investigate Malaria Parasites
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DOI: 10.1002/cbic.202000882
Abstract: Parasitic diseases like malaria tropica have been shaping human evolution and history since the beginning of mankind. After infection, the response of the human host ranges from asymptomatic to severe and may culminate in death.… read more here.
Keywords: chemical biology; investigate malaria; biology tools; biology ... See more keywords
When Supramolecular Chemistry Meets Chemical Biology: New Strategies to Target Proteins through Host‐Guest Interactions
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DOI: 10.1002/cbic.202100357
Abstract: Supramolecular chemistry for targeting proteins is of great interest for the development of novel approaches to recognize, isolate and control proteins. Taking advantage of chemical biology approaches, such as genetic‐code expansion and enzyme‐mediated ligation, guest… read more here.
Keywords: meets chemical; chemical biology; chemistry meets; chemistry ... See more keywords
SCF‐ChemBio: Chemical Biology Tour de France
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DOI: 10.1002/cbic.202300075
Abstract: Chemical biology is a steadily growing field that has traditionally struggled to clearly define its boundaries in a short sentence. However, it can be stated that through the development of chemical and physicochemical tools, concepts… read more here.
Keywords: chemical biology; scf chembio; biology tour; chembio chemical ... See more keywords
Chemical Biology Approaches toward Precise Structure Control of IgG‐Based Antibody‐Oligonucleotide Conjugates
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DOI: 10.1002/cbic.202300077
Abstract: Antibody‐oligonucleotide conjugates (AOCs) are important tools for drug development and biochemical analysis. However, the structural heterogeneity of AOCs synthesized through conventional coupling methods raises reproducibility and safety concerns in clinical trials. To address these issues,… read more here.
Keywords: chemical biology; control; antibody oligonucleotide; oligonucleotide conjugates ... See more keywords
PSL Chemical Biology Symposia Third Edition: A Branch of Science in its Explosive Phase
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DOI: 10.1002/cbic.202300093
Abstract: This symposium is the third PSL (Paris Sciences & Lettres) Chemical Biology meeting (2016, 2019, 2023) held at Institut Curie. This initiative originally started at Institut de Chimie des Substances Naturelles (ICSN) in Gif‐sur‐Yvette (2013,… read more here.
Keywords: chemical biology; institut curie; edition; psl chemical ... See more keywords
An Active Member of the EFMC: The Division of Medicinal Chemistry and Chemical Biology of the Swiss Chemical Society **
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DOI: 10.1002/cmdc.202300014
Abstract: The Division of Medicinal Chemistry and Chemical Biology (DMCCB) of the Swiss Chemical Society is an active contributor to the dynamics of the Swiss and European scientific communities. Founded in 1987, it pursues its mission… read more here.
Keywords: chemical biology; medicinal chemistry; chemistry; chemistry chemical ... See more keywords
A Personal Perspective on Chemical Biology: Before the Beginning
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DOI: 10.1002/ijch.201800171
Abstract: This perspective represents a brief personal account of early days before “chemical biology” emerged as a field of inquiry. Imagine a time when oligomers of DNA could not be synthesized and the order of the… read more here.
Keywords: biology; perspective chemical; personal perspective; chemical biology ... See more keywords
Chemical Biology Approaches to Understanding Neuronal O–GlcNAcylation
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DOI: 10.1002/ijch.202200071
Abstract: O-linked β-N-acetylglucosamine (O–GlcNAc) is a ubiquitous post-translational modification in mammals, decorating thousands of intracellular proteins. O–GlcNAc cycling is an essential regulator of myriad aspects of cell physiology and is dysregulated in numerous human diseases. Notably,… read more here.
Keywords: neuronal glcnacylation; chemical biology; biology approaches; biology ... See more keywords