Transcriptome analysis reveals brown adipogenic reprogramming in chemical compound-induced brown adipocytes converted from human dermal fibroblasts
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DOI: 10.1038/s41598-021-84611-0
Abstract: Brown adipogenesis contributes to controlling systemic energy balance by enhancing glucose and lipid consumptions. We have previously reported chemical compound-induced brown adipocytes (ciBAs) directly converted from human dermal fibroblasts using a serum-free medium. In this… read more here.
Keywords: converted human; analysis; chemical compound; brown adipocytes ... See more keywords
Chemical compound-based direct reprogramming for future clinical applications
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DOI: 10.1042/bsr20171650
Abstract: Recent studies have revealed that a combination of chemical compounds enables direct reprogramming from one somatic cell type into another without the use of transgenes by regulating cellular signaling pathways and epigenetic modifications. The generation… read more here.
Keywords: cell; direct reprogramming; chemical compound; future clinical ... See more keywords