Determination of steroids in bovine hair: validation of a microwave-assisted chemical derivatization method using LC-MS/MS and in vivo studies.
Sign Up to like & getrecommendations! Published in 2020 at "Drug testing and analysis"
DOI: 10.1002/dta.2815
Abstract: Hair analysis has attracted great attention in regulatory analysis of food producing animals, especially due to the wider detection window of veterinary drugs in this matrix and also to the possibility of confirming parent drugs… read more here.
Keywords: validation; bovine hair; method; microwave assisted ... See more keywords
A Combined Chemical Derivatization/Mass Spectrometric Method for the Enhanced Detection and Relative Quantification of Protein Ubiquitination.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9232-4_2
Abstract: Mass spectrometry (MS) is a sensitive analytical technique with wide application across the sciences including for the detection of peptides and proteins in biological analysis. Ubiquitinated (Ub) proteins are typically analyzed by proteolytic digestion and… read more here.
Keywords: detection; combined chemical; mass; method ... See more keywords
Recent developments of novel matrices and on-tissue chemical derivatization reagents for MALDI-MSI
Sign Up to like & getrecommendations! Published in 2020 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-020-03023-7
Abstract: Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) is a fast-growing technique for visualization of the spatial distribution of the small molecular and macromolecular biomolecules in tissue sections. Challenges in MALDI-MSI, such as poor sensitivity for… read more here.
Keywords: chemistry; tissue chemical; maldi msi; developments novel ... See more keywords
A LysargiNase- and chemical derivatization-based strategy LAACTer facilitating in-depth profiling of C-terminome.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b03543
Abstract: Global identification of protein C-termini is highly challenging due to their low abundance in conventional shotgun proteomics. Several enrichment strategies has been developed to facilitate the detection of C-terminal peptides. One major issue of previous… read more here.
Keywords: depth; lysarginase chemical; terminome; chemical ... See more keywords
Chemical Derivatization of Affinity Matrices Provides Protection from Tryptic Proteolysis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.9b00254
Abstract: The enrichment of biotinylated proteins using immobilized streptavidin has become a staple methodology for affinity purification-based proteomics. Many of these workflows rely upon tryptic digestion to elute streptavidin-captured moieties from the beads. The concurrent release… read more here.
Keywords: affinity matrices; proteolysis; affinity; streptavidin ... See more keywords
Chemical Derivatization of Commercially Available Condensed and Hydrolyzable Tannins
Sign Up to like & getrecommendations! Published in 2021 at "ACS Sustainable Chemistry & Engineering"
DOI: 10.1021/acssuschemeng.1c02114
Abstract: Novel valorization routes for tannins were opened by the development of a simple, straightforward, robust, and flexible approach to the selective functionalization of condensed and hydrolyzable tannins. Irrespective of the different degrees of polymerization, different… read more here.
Keywords: derivatization commercially; available condensed; hydrolyzable tannins; condensed hydrolyzable ... See more keywords