Prioritization of Contaminants of Emerging Concern in Wastewater Treatment Plant Discharges Using Chemical:Gene Interactions in Caged Fish.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental science & technology"
DOI: 10.1021/acs.est.7b01567
Abstract: We examined whether contaminants present in surface waters could be prioritized for further assessment by linking the presence of specific chemicals to gene expression changes in exposed fish. Fathead minnows were deployed in cages for… read more here.
Keywords: gene; chemical gene; gene expression; treatment plant ... See more keywords
Predictive Analysis Using Chemical-Gene Interaction Networks Consistent with Observed Endocrine Activity and Mutagenicity of U.S. Streams.
Sign Up to like & getrecommendations! Published in 2019 at "Environmental science & technology"
DOI: 10.1021/acs.est.9b02990
Abstract: In a recent U.S. Geological Survey/U.S. Environmental Protection Agency study assessing >700 organic compounds in 38 streams, in vitro assays indicated generally low estrogen, androgen, and glucocorticoid receptor activities, with 13 surface waters with 17β… read more here.
Keywords: observed endocrine; analysis; chemical gene; mutagenicity ... See more keywords
A global network of biomedical relationships derived from text
Sign Up to like & getrecommendations! Published in 2018 at "Bioinformatics"
DOI: 10.1093/bioinformatics/bty114
Abstract: Motivation: The biomedical community's collective understanding of how chemicals, genes and phenotypes interact is distributed across the text of over 24 million research articles. These interactions offer insights into the mechanisms behind higher order biochemical… read more here.
Keywords: network; disease; chemical gene; gene disease ... See more keywords