Articles with "chemical genomics" as a keyword



Photo by mybbor from unsplash

Chemical Genomics, Structure Elucidation, and in Vivo Studies of the Marine-Derived Anticlostridial Ecteinamycin.

Sign Up to like & get
recommendations!
Published in 2017 at "ACS chemical biology"

DOI: 10.1021/acschembio.7b00388

Abstract: A polyether antibiotic, ecteinamycin (1), was isolated from a marine Actinomadura sp., cultivated from the ascidian Ecteinascidia turbinata. 13C enrichment, high resolution NMR spectroscopy, and molecular modeling enabled elucidation of the structure of 1, which… read more here.

Keywords: vivo; structure elucidation; chemical genomics; structure ... See more keywords
Photo by ldxcreative from unsplash

ChemGAPP: a tool for chemical genomics analysis and phenotypic profiling

Sign Up to like & get
recommendations!
Published in 2023 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btad171

Abstract: Abstract Motivation High-throughput chemical genomic screens produce informative datasets, providing valuable insights into unknown gene function on a genome-wide level. However, there is currently no comprehensive analytic package publicly available. We developed ChemGAPP to bridge… read more here.

Keywords: chemical genomics; chemgapp; screens chemgapp; chemgapp tool ... See more keywords
Photo by nci from unsplash

Advances in fungal chemical genomics for the discovery of new antifungal agents

Sign Up to like & get
recommendations!
Published in 2020 at "Annals of the New York Academy of Sciences"

DOI: 10.1111/nyas.14484

Abstract: Invasive fungal infections have escalated from a rare curiosity to a major cause of human mortality around the globe. This is in part due to a scarcity in the number of antifungal drugs available to… read more here.

Keywords: fungal chemical; new antifungal; discovery new; chemical genomics ... See more keywords