Conjugation of chemical handles and functional moieties to DNA during solid phase synthesis with sulfonyl azides
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DOI: 10.1093/nar/gkac566
Abstract: Abstract Labelling of oligonucleotides with dyes, targeting ligands, and other moieties has become ever more essential in life-sciences. Conventionally, modifications are introduced to oligonucleotides during solid phase synthesis by special phosphoramidites functionalised with a chemical… read more here.
Keywords: phase synthesis; synthesis; solid phase; chemical handles ... See more keywords